APPLICATION OF THE TIME-RESOLVED MICROSCOPY TO THE INVESTIGATION OF SUBCELLULAR HYPERTHERMIA
https://doi.org/10.56304/S2079562925010130
EDN: EUYUAC
Abstract
In this paper, the regularities of laser heating of iron oxide nanoparticles depending on their size, shape, and aggregation at the subcellular level were investigated. The temperature was measured using time-resolved fluorescence thermometry based on rhodamine B dye. The obtained temperature estimates are over 100°C, which creates favorable conditions for initiation of programmed cell death of tumor cells at laser hyperthermia.
About the Authors
I. V. Markova
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation
Russian Federation
A. V. Ryabova
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute);
Prokhorov General Physics Institute, Russian Academy of Sciences
Russian Federation
Russian Federation
D. V. Pominova
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute);
Prokhorov General Physics Institute, Russian Academy of Sciences
Russian Federation
Russian Federation
I. D. Romanishkin
Prokhorov General Physics Institute, Russian Academy of Sciences
Russian Federation
Russian Federation
K. G. Linkov
Prokhorov General Physics Institute, Russian Academy of Sciences
Russian Federation
Russian Federation
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Review
For citations:
Markova I.V., Ryabova A.V., Pominova D.V., Romanishkin I.D., Linkov K.G. APPLICATION OF THE TIME-RESOLVED MICROSCOPY TO THE INVESTIGATION OF SUBCELLULAR HYPERTHERMIA. Nuclear Physics and Engineering. 2025;16(5):715-720. (In Russ.) https://doi.org/10.56304/S2079562925010130. EDN: EUYUAC
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