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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">npe</journal-id><journal-title-group><journal-title xml:lang="ru">Ядерная физика и инжиниринг</journal-title><trans-title-group xml:lang="en"><trans-title>Nuclear Physics and Engineering</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-5629</issn><issn pub-type="epub">2079-5637</issn><publisher><publisher-name>МИФИ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.56304/S2079562924050348</article-id><article-id custom-type="elpub" pub-id-type="custom">npe-369</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Физика наноструктур</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Physics of Nanostructures</subject></subj-group></article-categories><title-group><article-title>МУЛЬТИФЕРМЕНТАТИВНАЯ АКТИВНОСТЬ СТАБИЛИЗИРОВАННЫХ МАЛЬТОДЕКСТРИНОМ НАНОЧАСТИЦ ДИОКСИДА ЦЕРИЯ, ДОПИРОВАННЫХ РЕДКОЗЕМЕЛЬНЫМИ ЭЛЕМЕНТАМИ</article-title><trans-title-group xml:lang="en"><trans-title>Multienzymatic Activity of Maltodextrin-Coated Cerium Dioxide Nanoparticles Doped with Rare Earth Elements</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Офицерова</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ofitserova</surname><given-names>N. Yu.</given-names></name></name-alternatives><email xlink:type="simple">n.ofitserova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бажукова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhukova</surname><given-names>I. N.</given-names></name></name-alternatives><email xlink:type="simple">n.ofitserova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский федеральный университет имени первого Президента России Б.Н. Ельцина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Federal University named after the First President of Russia B.N. Yeltsin</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2024</year></pub-date><volume>15</volume><issue>5</issue><fpage>498</fpage><lpage>503</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Офицерова Н.Ю., Бажукова И.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Офицерова Н.Ю., Бажукова И.Н.</copyright-holder><copyright-holder xml:lang="en">Ofitserova N.Y., Bazhukova I.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://npe.elpub.ru/jour/article/view/369">https://npe.elpub.ru/jour/article/view/369</self-uri><abstract><p>Нанокристаллический диоксид церия является перспективным материалом с точки зрения биомедицинских применений благодаря своей способности выполнять функции различных ферментов и инактивировать свободные радикалы. Одним из способов тонкой настройки физико-химических свойств наночастиц и проявляемой активности является модификация структуры кристаллической решетки в результате допирования ионами трехвалентных редкоземельных элементов. В работе изучены пероксидазная и оксидазная активности, а также способность инактивировать гидроксильный радикал для чистых и допированных наночастиц диоксида церия, покрытых стабилизирующей мальтодекстриновой оболочкой.</p></abstract><trans-abstract xml:lang="en"><p>Nanocrystalline cerium dioxide is a promising material for biomedical applications due to its ability to perform the functions of various enzymes and inactivate free radicals. One of the ways to tune the physicochemical properties of nanoparticles and its biocatalytic activity is to modify the crystal lattice structure by means of doping with trivalent rare earth ions. Peroxidase, oxidase activity, and the ability to inactivate the hydroxyl radical by pure and doped maltodextrin-coated cerium dioxide nanoparticles are studied in the present paper.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>наноматериалы</kwd><kwd>диоксид церия</kwd><kwd>редкоземельные элементы</kwd><kwd>допирование</kwd><kwd>мальтодекстрин</kwd><kwd>свободные радикалы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nanomaterials</kwd><kwd>cerium dioxide</kwd><kwd>rare earth elements</kwd><kwd>doping</kwd><kwd>maltodextrin</kwd><kwd>free radicals</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Авторы выражают благодарность Е.О. Бакшееву и М.А. Машковцеву за образцы, предоставленные для исследования; А.С. Фарленкову и Н. Пизуровой за помощь в проведении экспериментальной работы по аттестации исследуемых объектов.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta A., Das S., Neal C., et al. // J. Mater. Chem. 2016. V. 4 (19). P. 3195–3202.</mixed-citation><mixed-citation xml:lang="en">Gupta A., Das S., Neal C., et al. // J. Mater. Chem. 2016. V. 4 (19). P. 3195–3202.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Balamurugan A., Sudha M., Surendhiran S. // Mater. Today: Proc. 2019. V. 26 (1). P. 1–7.</mixed-citation><mixed-citation xml:lang="en">Balamurugan A., Sudha M., Surendhiran S. // Mater. Today: Proc. 2019. V. 26 (1). 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